reticularis – the site of sex hormone production (i.e. DHEA, androstenedione)
The adrenal glands are unique in that part of them, the inner adrenal medulla, has a direct connection to the brain. As the adrenals become more exhausted then the symptoms get stronger and affect all zones.
Overactive adrenal glands usually produce too much cortisol and possibly other adrenal hormones (i.e. epinephrine, aldosterone) leading to increased blood sugar level and in time to conditions like insulin resistance and metabolic syndrome.
Underactive adrenal glands, on the other hand, produce inadequate amounts of hormones, especially cortisol, to maintain homeostasis in the body. A common clinical problem with underactive adrenal glands is hypoglycemic symptoms due to fluctuations in blood sugar. When cortisol is unavailable, glucose levels get too low. This causes the lightheadedness, shakiness and irritability that people with low blood sugar experience, and is why people with low blood sugar commonly wake up during the night.
If you feel tired all the time, sweat excessively or wake up and cannot get back to sleep, you may be suffering from adrenal stress also often called adrenal exhaustion. Other symptoms include include tiredness, insomnia, anxiety, low blood pressure, muscle pain, multiple chemical sensitivity, food allergies, loss of libido, low body temperature, low energy, menstrual irregularities, insomnia, PMS, sluggishness, heart palpitations, salt craving and hypoglycemia.and loss of appetite are just some of the concerns associated with higher than normal levels of cortisol. Cortisol is naturally lower during sleep.
In addition to the symptoms, many recognized conditions are related to or conditioned by adrenal fatigue, including IBS, depression, metabolic syndrome, type 2 diabetes, hypotension, other hormonal dysfunctions, and auto-immune diseases.
Co-enzyme Q10 (ubiquinone) may ease symptoms of brain fog and may be necessary to support any remedial treatment because at cellular level the organ may be low in ATP. Small regular high protein meals may support the adrenals. Siberian ginseng or Rhodiola,or other glandulars may increase the capacity of the adrenals but other adaptogenics can increase exhaustion. High levels of Vitamin B5(pantothenic acid) and vitamin C are also supportive nutrients for adrenal health. It is considered that poor adrenals are often accompanied by poor digestion and absorption of proteins. Other nutrients that affect the performance of the adrenals include Vitamin D, magnesium and L-tyrosine. Additions of hyrolysed collagen or free form amino acids can increase adrenal functioning.